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2025/12/22(Mon) 11:34
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The extra steps required by GLP are unnecessary, and can add to both cost and duration of a study. A study done on rodents found that chronic administration of PYY reduced adiposity and made them resistant to diet-induced obesity.(2) PYY analogues are currently being tested as weight loss drugs. GLP-1 receptors agonist such as liraglutide is approved by the FDA for the treatment of obesity and has shown to cause significant weight loss in conjunction with a reduced calorie diet and increased physical activity.(3) Similarly, PYY analogues are also being tested as potential weight loss drugs. Drugs mimicking the effects of these hormones such as GLP1 receptors and agonists and PYY analogues have been developed and are being used currently in clinical trials to know about their ability to promote weight loss. Such investigations may further improve the development and the usage of GLP-1-based drugs. The authors also emphasized that the wider use of these drugs should consider social and commercial determinants of health, including access, affordability and insurance coverage, to avoid deepening existing health inequities among people living with obesity. A GLP-1 receptor agonist, liraglutide, has been approved by the FDA for the treatment of obesity and has been shown to cause significant weight loss in conjunction with a reduced calorie diet and increased physical activity.
2025/12/22(Mon) 11:34
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2025/12/22(Mon) 11:34
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